Pharmaceutical

Gilson, Inc., a global leader in preparative HPLC, offers a full line of chromatographic instruments to suit the needs of today’s scientist in the purification market. From robust instruments for reformatting techniques to complicated assay procedures with disposable tip or fixed probe options, Gilson has an automated solution to meet your liquid handling application requirements.

Purification of Vanillin by a Combination of Flash and Preparative HPLC with the PLC 2250

keyword: Vanillin, Vanilla Extract, PLC Purification Systems, FLASH Chromatography, Preparative HPLC.

Selecting the Appropriate Laboratory Equipment: The Coomassie (Bradford) Protein Assay Performed Manually using Gilson PIPETMAN® M Multichannel, PIPETMAN L, and Automated using GX-271 ASPEC® and GX-241 Liquid Handler
	keyword: PIPETMAN® L, PIPETMAN M Multichannel, GX-241 Liquid Handler, GX-274 ASPEC®, Coomassie (Bradford) Protein Assay, Molecular Biology, Automation, Laboratory Equipment Download

An Undergraduate's Approach to Method Development: Chromatography Lessons Learned through Experimentation
	keyword: PLC 2020, Purification, Preparative Chromatography, Reversed Phase Chromatography, Method Development, Sparation Science, Pharmaceuticals Download

Manual Automation of Rapid N-Glycan Sample Preparation - Reliable Results from Error Free Sample Tracking and Accurate Pipetting
	keyword: N-Glycan, Glycobiology, hlgG, Sample Cleanup, Purification, Glycoanalysis, Microchromatography Download

Urification and Analysis of Bioactive Extracts from Marine Yeast with the Gilson Semi-Micro 2D HPLC System
	keyword: 2D HPLC (2 Dimensional High Pressure Liquid Chromatography), TRILUTION LC Liquid Chromatography Software, Gilson 233XL, Bioactive, Marine Yeast Download

Automated Separation of Crude Extracts from Natural Products into Fractions for Primary High Throughput Screening
	keyword: Gilson 215 Liquid Chromatography System, TRILUTION LC Liquid Chromatography Software, High Throughput Screening, Natural Products Download

Natural Product Purification of Lycopene and B-Carotene Using Flash Column Sample Clean-up Prior to High Pressure Normal Phase Chromatography on the Gilson PLC 2020
	keyword: PLC 2020, Natural Product Purification, Flash Chromatography, Lycopene, Tea, B-Carotene, Tomatoes Download

A Quick Study - Comparison of Chromatography Normal Phase vs. Flash on the Gilson PLC 2020
	keyword: Purification, Normal Phase Chromatography, Flash Chromatography, PLC 2020, Preparative Chromatography Download

Improving Laboratory Efficiency & Flexibility with Automated Sample Preparation Systems - The Impact of the GX-281 Dual Z-Arm Weighing Station
	keyword: Weighing Station, GX-281 Liquid Handler, Sample Preparation, Automated Systems, Bar Coding, Tube Gripper, TRILUTION LH v3.0 Liquid Handling Software Download

Automated Solid Phase Extraction (SPE) of Benzodiazepines from Urine using the Gilson GX-274 ASPEC®
	keyword: Gilson GX-274 ASPEC®, TRILUTION® LH, Solid Phase Extraction (SPE), LC/MS-MS Analysis,Diazepam, Benzodiazepines, Urine, Pharmaceuticals Download

A Practical User Guide for the Determination of Optimal Purification Gradients for the Gilson PLC 2020
	keyword: Purification, Pharmaceuticals, Optimal Solvent Gradients, Isolation Gradients, Organic Compounds, PLC 2020, Preparative Chromatography Download

Automated Determination of VMA, HVA, 5-HIAA, in Urine Using the Gilson GX-274 and Gilson ASPEC® XL
	keyword: Gilson GX-274, TRILUTION® LH, Catecholamines, Urine, Vanillylmandelic acid (VMA), Homovanilic Acid (HVA), 5-hydroxyindoleacetic Acid (5-HIAA), Tumors, Diagnosis, Biosyntheses, Recipe Download

Rapid Isolation of Geraniin from Nephelium Lappaceum Rind Waste Using the Gilson GX-281 Preparative HPLC Purification System
	keyword: Gilson GX-281 Preparative HPLC System, TRILUTION® LC, Geraniin, Alpha Glucosidase, Alpha Amylase, Aldol Reductase, AGE, Nephelium Lappaceum L., University of Malaysia, Anti-Hyperglycemic Agent, Hyperglycemia, Purification, Natural Products, HPLC, Diabetes Download

Identifying and Collecting Weak UV Absorbance and Low Level Peaks of Interest From a Complex Mixture Using Conditional Logic Purification on Mass and UV Signals
	keyword: Gilson GX-271 LC/MS Purification System, Fraction Collection, Active Pharmaceutical Ingredient (API), Metoprolol, Verapamil, Chloramphenicol, Doxepin, Sulfamethazine Download

Processing Human Serum for Rapid and Reproducible N-Glycan Mass Profiling
	keyword: Automation, Biomarkers, Glycans, Glycomics, GX-274 ASPEC, Human Serum, Mass Profiling, Mass Spectrometry, MALDI-FTICR, MS, N-Glycan, N-linked Glycans, Serum, Solid Phase Extraction, SPE Download

Optimizing the Purification of a Standard Chrial Compound Utilizing a Benchtop, Multi-Purpose, Semi-Preparative to Preparative HPLC System
	keyword: Chiral, Enantiomer, HPLC, Normal Phase Chromatography, PLC 2020 Personal Chromatography System, Preparative Chromatography, Purification, Resolution, Trans-Stilbene Oxide Download

Automated Solid Phase Extraction of Allantoin from Cosmetics and Topical Pharmaceuticals Prior to Analysis by HPLC
	keyword: Allantoin, Automation, CHROMABOND HR-XA, Cosmetics Glyoxylic Acid Diureide, GX-271 ASPEC, HILIC, HPLC, Ointments, Pharmaceuticals, Sample Preparation, Sold Phase Extraction, SPE, Topical Pharmaceuticals, 5-Ureidohydantoin Download

FTLC Fraction Trapping Liquid Chromatography
	keyword: HPLC, Preparative Chromotography, Gilson FT-LC System Download

Automated Fractionation System that Increases Recovery and Optimizes Precision of Solid Phase Extraction Methodology
	keyword: Solid Phase Extraction, SPE, Serum, Plasma, Urine Download

A Novel Approach to GX-281 Semi-Preparative System Purification of Natural Compounds Using Isolation Gradients
	keyword: GX-281 Purification System, TRILUTION LC, natural compounds, Oregano, Rosmarinic Acid, Carvacol, isolation gradient, purification, fraction collection Download

Systematic Look at the Affects of Various Solvents, Injection Techniques and Sample Amounts on Preparative HPLC Columns
	keyword: Various Solvents, Injection Techniques, Solvents Download

A Totally Automated Solution for Normal and RP Preparative HPLC with Analytical Purification Determination: cLC
	keyword: Analytical Purification Determination, cLC System, Reverse-Phase (RP) Chromatography, Normal Phase (NP) Chromatography Download

A Compact Automated Liquid Handler for Microbatch Protein Crystallography
	keyword: Protein Crystallization, Microbatch Download

A Multipurpose Preparative System for the Detection and Collection of Active and Non-active UV/VIS Compounds
	keyword: Active and Non-Active UV/VIS Compounds, ELSD Download

An Automated SPE Procedure and Analysis for the Extraction of Chlorpromazine and Thiorizidine from Plasma
	keyword: Neuroleptic Drugs, SPE, SPE 215 Download

Purification of Vanillin by a Combination of Flash and Preparative HPLC with the PLC 2250

Streamlined Purification of Assay-ready Oligonucleotides by Automated HPLC

Automated Purification and Analytical Reinjection of a Small Molecule Drug, Probenecid, on a Gilson LC/MS Dual Function System

Evaluation of Ketone-Containing Terpene Compounds Using Evaporative Light Scattering Detection

Automating the Promega GoTaq® PCR Core System II Reaction Using the Gilson PIPETMAX® 268

High-Resolution Purification of Sheared Lambda Phage DNA Using a Gilson HPLC System

Automated Patient Barcode Tracking and Sample Preparation Using the Gilson GX-281 Barcode Matching System

Recovery and Purification Comparison of Glycinin Using Various pH Extraction Procedures on a Continuous Injection Gradient Gilson PLC 2020 System

Purification of Aglain Natural Products with the Gilson PLC 2020 Personal Purification System

Isolation of Synthetic Pleiomaltinine Using the Gilson PLC 2020 Personal Purification System

Selecting the Proper Pipetting Tools for Optimal PCR and qPCR in the Laboratory

Determination of Pesticides in Drinking Water via LC-MS/MS Using Polymeric Solid Phase Extraction Cartridges

Efficient LC-MS/MS Method for Determination of delta9-Tetrahydrocannabinol in Human Plasma Using Solid Phase Extraction Clean-up

Methamphetamine and Amphetamine Drug Screening in Urine via Solid Phase Extraction

Optimizing Chiral Separations and Purification of Enantiomers through Selective Sample Slicing and Column Switching

Natural Product Purification: Bioactive trans-Cinnamaldehyde from Zingiberaceae Extract for Use as a Skin Lightening Agent

High Loading Purification of a Ribonuclease A Protein Using a Manual Purification System

Purification of a Protein Using the PLC 2020 Personal Purification System

Purification of the B-Lactoglobulin A Protein with the Gilson GX-271 LC/MS Purification System

Scale-Up of a 6-mer Synthesized Peptide Using a Manual HPLC System

Preparative Purification of a Synthesized Peptide Using an Automated LC/MS Purification System

Purification of a 25-mer ssDNA Oligonucleotide Using the PLC 2020 Personal Purification System

Selecting the Appropriate Laboratory Equipment: The Coomassie (Bradford) Protein Assay Performed Manually using Gilson PIPETMAN® M Multichannel, PIPETMAN L, and Automated using GX-271 ASPEC® and GX-241 Liquid Handler

An Undergraduate's Approach to Method Development: Chromatography Lessons Learned through Experimentation

Manual Automation of Rapid N-Glycan Sample Preparation - Reliable Results from Error Free Sample Tracking and Accurate Pipetting

Urification and Analysis of Bioactive Extracts from Marine Yeast with the Gilson Semi-Micro 2D HPLC System

Automated Separation of Crude Extracts from Natural Products into Fractions for Primary High Throughput Screening

Natural Product Purification of Lycopene and B-Carotene Using Flash Column Sample Clean-up Prior to High Pressure Normal Phase Chromatography on the Gilson PLC 2020

A Quick Study - Comparison of Chromatography Normal Phase vs. Flash on the Gilson PLC 2020

Improving Laboratory Efficiency & Flexibility with Automated Sample Preparation Systems - The Impact of the GX-281 Dual Z-Arm Weighing Station

Automated Solid Phase Extraction (SPE) of Benzodiazepines from Urine using the Gilson GX-274 ASPEC®

A Practical User Guide for the Determination of Optimal Purification Gradients for the Gilson PLC 2020

Automated Determination of VMA, HVA, 5-HIAA, in Urine Using the Gilson GX-274 and Gilson ASPEC® XL

Rapid Isolation of Geraniin from Nephelium Lappaceum Rind Waste Using the Gilson GX-281 Preparative HPLC Purification System

Identifying and Collecting Weak UV Absorbance and Low Level Peaks of Interest From a Complex Mixture Using Conditional Logic Purification on Mass and UV Signals

Optimizing the Purification of a Standard Chrial Compound Utilizing a Benchtop, Multi-Purpose, Semi-Preparative to Preparative HPLC System

Automated Solid Phase Extraction of Allantoin from Cosmetics and Topical Pharmaceuticals Prior to Analysis by HPLC

Processing Human Serum for Rapid and Reproducible N-Glycan Mass Profiling

FTLC Fraction Trapping Liquid Chromatography

Automated Fractionation System that Increases Recovery and Optimizes Precision of Solid Phase Extraction Methodology

A Novel Approach to GX-281 Semi-Preparative System Purification of Natural Compounds Using Isolation Gradients

Systematic Look at the Affects of Various Solvents, Injection Techniques and Sample Amounts on Preparative HPLC Columns

A Totally Automated Solution for Normal and RP Preparative HPLC with Analytical Purification Determination: cLC

A Compact Automated Liquid Handler for Microbatch Protein Crystallography

A Multipurpose Preparative System for the Detection and Collection of Active and Non-active UV/VIS Compounds

An Automated SPE Procedure and Analysis for the Extraction of Chlorpromazine and Thiorizidine from Plasma

Fast PCLC: A Widely Application Technique for Laboratory Scale Preparative Separations

An Automated SPE Procedure and Analysis for the Determination of Ibuprofen and Ketoprofen from Plasma

The Ephedra Story: An Automated SPE Procedure and Analysis for the Determination of Ephedra and Ephedra-like Compounds in Foods and Dietary Supplements

Automated Preparation of MALDI-TOF Plates via a Spring-Loaded Probe

Fast PCLC: A Widely Application Technique for Laboratory Scale Preparative Separations
	keyword: Fast PCLC Download

An Automated SPE Procedure and Analysis for the Determination of Ibuprofen and Ketoprofen from Plasma
	keyword: SPE, Ketoprofen, Ibuprofen, Prostaglandin Download

The Ephedra Story: An Automated SPE Procedure and Analysis for the Determination of Ephedra and Ephedra-like Compounds in Foods and Dietary Supplements
	keyword: Ephedra, Norephedrine, Pseudoephedrine, Methylephedrine, Dietary Supplements, Nutraceuticals, Gilson SPE 215 Download

Automated Preparation of MALDI-TOF Plates via a Spring-Loaded Probe
	keyword: 223 Sample Changer, Matrix Assisted Laser Desorption/Ionization (MALDI), peptide, MALDI-TOF MS, bradykinin, angiotensin II, ACTH, a-cyano-4-hydroxycinnamic acid, Bruker AnchorChip Download